| Year | W | L | Sv | Hold | IP | H | BB | SO | ER | ERA | WHIP | Rate |
| 2026 proj | 7 | 7 | 0 | 0 | 116.0 | 113 | 45 | 102 | 59 | 4.58 | 1.365 | 11.2 |
| 2025 | 7 | 3 | 0 | 0 | 76.3 | 70 | 35 | 70 | 32 | 3.77 | 1.376 | 23.9 |
| 2024 | 6 | 13 | 0 | 0 | 171.7 | 174 | 66 | 130 | 99 | 5.19 | 1.398 | -9.0 |
| 2023 | 7 | 8 | 0 | 0 | 127.0 | 121 | 36 | 139 | 61 | 4.32 | 1.236 | 24.9 |
| Date | News |
| 3/03/26 | Padres notebook: Griffin Canning gets on backfield mound; Logan Gillaspie a real possibility in pen. Newcomer Griffin Canning won't begin the season with the Padres, but his being in rotation is only a matter of time. Source: https://www.sandiegouniontribune.com/2026/03/03/pa... |
| 2/14/26 | Padres address needs by adding Griffin Canning and Nick Castellanos. Team needed veteran starting pitcher and a hitter; Canning likely to join rotation in May or June Source: https://www.sandiegouniontribune.com/2026/02/14/pa... |
| 2/14/26 | Padres address needs by adding Griffin Canning and Nick Castellanos. Team needed veteran starting pitcher and a hitter Source: https://www.sandiegouniontribune.com/2026/02/14/pa... |
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