| Year | W | L | Sv | Hold | IP | H | BB | SO | ER | ERA | WHIP | Rate |
| 2026 proj | 10 | 9 | 0 | 0 | 155.0 | 147 | 40 | 145 | 69 | 4.01 | 1.206 | 33.7 |
| 2024 | 6 | 5 | 0 | 0 | 99.7 | 94 | 23 | 101 | 42 | 3.79 | 1.174 | 30.6 |
| 2023 | 10 | 3 | 0 | 0 | 97.3 | 90 | 21 | 97 | 33 | 3.05 | 1.140 | 47.8 |
| 2022 | 10 | 7 | 0 | 0 | 181.0 | 154 | 42 | 184 | 59 | 2.93 | 1.083 | 77.8 |
| Date | News |
| 3/16/26 | Padres' Musgrove likely to open season on IL. San Diego Padres starter Joe Musgrove is expected to open this season on the injured list while still working to come back from Tommy John surgery that kept him from pitching last year. Source: https://www.espn.com/mlb/story/_/id/48225703/padre... |
| 3/04/26 | Joe Musgrove was all he could be in spring debut, return from Tommy John. Padres right-hander worked into the third inning, struggled with command but had good life on pitches Source: https://www.sandiegouniontribune.com/2026/03/04/qu... |
| 3/02/26 | Padres notebook: Different looks for Jake Cronenworth; Joe Musgrove to face Brits; Matt Waldron update. Padres searching for lead-off hitter, backup shortstop. Source: https://www.sandiegouniontribune.com/2026/03/02/pa... |
| 2/26/26 | Joe Musgrove sharp in simulated game; Cactus League start could be next. Right-hander who missed 2024 season following Tommy John surgery was happy to work through fatigue while throwing 36 pitches Source: https://www.sandiegouniontribune.com/2026/02/26/jo... |
| 1/25/26 | Padres’ Joe Musgrove ready to go with eye toward healthy season. Starting pitcher speaks about upcoming season after losing 2025 to Tommy John surgery. Source: https://www.sandiegouniontribune.com/2026/01/25/pa... |
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